To: *@yahoo.com.cn, *@sina.com.cn From: jam@oxon.blackwellpublishing.com Date: 02 Dec 2005 CC: Subject: Journal of Applied Microbiology - JAM-2005-1303 02 Dec 2005 Dear Dr. * Manuscript: JAM-2005-1303 Title: * Author(s): * Thank you for submitting the above manuscript to Journal of Applied Microbiology. Your manuscript has been reviewed and I am sorry to have to inform you that, as currently presented, it is not suitable for publication in the journal. However, you are encouraged to modify your manuscript taking into account the reviewers’comments, in which case the Editors would be willing to reconsider and I will be pleased to receive a revised manuscript. The revised paper will be reviewed once more and the decision of the Editors is final. If you decide to submit a revised manuscript I should be grateful if you would include with your submission a detailed explanation of how you have dealt with the points raised by the referees. This must be entered into the fields entitled Response to Editor and Response to Reviewers which appear during online submission otherwise they will not be available to the handling editor and reviewers respectively. In addition, to help in assessing the reviewing process, please indicate any changes in the revised manuscript by using the highlighter tool in Word to highlight the changes in yellow. Before resubmitting your manuscript please also ensure that any artwork meets the criteria as outlined in the journal's instructions to authors, given in the weblink below. Please note that poor quality figures may delay the publication of your paper. http://www.blackwellpublishing.com/authors/digill.asp The revised manuscript should be uploaded via your corresponding author centre, at: http://appliedmicrobiology.manuscriptcentral.com Click on the 'revised manuscript' option and the title of your paper to submit your revised manuscript. Comments on technical aspects of your paper are included below: Yours sincerely Arthur Gilmour, Chief Editor, JAM EDITOR'S COMMENTS TO AUTHORS Dear authors, Upon careful consideration of the comments from both reviewers I believe it is important to address the issues raised about the description of some of your methods and more importantly discussion and hence I recommend a major revision before publication. However, I hope you will find the suggestions relatively striaghtforward to implement. Please make sure that you address all the points raised by both reviewers. COMMENTS FROM REFEREES: (Comments in attachment form should be accessed from your corresponding author centre) Reviewer 1 Comments: 1. General Comments：The Introduction clearly describes the background and significance of the