Multiphase Molecular Catalysis and Immobilization is gaining in significance as global society demands greener synthetic methodologies. Both academic and industrial chemists are meeting this challenge by applying a high level of scientific creativity to discover and develop efficient systems using "green" solvents and allowing catalyst recycling and easy product isolation. Because of the significance of Multiphase Molecular Catalysis and Immobilization for global society and the synergism of industrial and academic efforts, it is ideally suited as the subject for a special thematic issue of ASC. It is my pleasure to invite you on behalf of the Issue Editors to participate in this special issue by contributing a communication or full paper. The ASC Special Issue on Multiphase Molecular Catalysis and Immobilization will be appear in August 2006. To coordinate the timing of the issue with the other regular issues, the manuscript deadline is ***************************** 24 March 2006. ***************************** The scope includes aqueous phase catalysis, fluorous catalysis, other multiphase systems, supercritical fluids, ionic liquids, homogeneous catalysts supported on soluble (linear) polymers and dendrimers, micellar catalysis, microencapsulated catalysts, and immobilization of homogeneous catalysts on inorganic and on solid polymer supports. Metal, organic and enzyme catalysis all fall within the purview of the issue. The focus is on asymmetric catalysis, but non-catalytic and non- asymmetric methods are not taboo, when they constitute a significant advance in practical, efficient and environmentally friendly synthesis. Complex molecule and fine-chemical syntheses are welcome when multiphase catalysis and/or immobilization constitute a key step. Classical heterogeneous catalysis is not within the scope of this issue; the focus of this issue, as of ASC in general, is on "molecular catalysis" or what one might refer to "single-site catalysis". The goals of this issue will be (1) to present overviews both from the academic and industrial perspectives, (2) to present a broad spectrum of current research in the area in order familiarize the reader with the most exciting current developments and frontiers, (3) to foster information exchange and synergism between academia and industry, (4) to promote a broader application of these new methodologies in academic research and industrial application, and (5) to stimulate further developments. In short this will be a celebration of current achievements and future perspectives in this exciting field. The level of quality of this issue will be very high, for which all manuscripts will undergo strict peer review. Therefore, you are encouraged to report on new results from your laboratories that you consider to be important or very important to the field.